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The research for new products against pathogens, parasites, and infesting species implies huge scientific and economic efforts. Traditional approaches are based on random screening procedures searching for bioactive compounds from different sources. However, the development of new products, in most cases, has been limited by side effects on biological systems other than the target, environmental contamination, and by the induction of resistance in the organisms to be controlled. Consequently, despite the major and increasing efforts on research of new products in both agriculture and medicine, the rate of approval is significantly decreased in recent years.
The recent discovery of the inhibitory effect of extracellular self-DNA has opened new perspectives for highly species-specific inhibitory product for biological control, with relevant economic and environmental advantages.